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English to Spanish: TWO WAYS CONVALESCENT PLASMA COULD HELP FIGHT COVID-19 General field: Medical Detailed field: Medical (general)
Source text - English TWO WAYS CONVALESCENT PLASMA COULD HELP FIGHT COVID-19
Blood plasma from people who have recovered from COVID-19 could be a key part of the fight against the disease because it contains antibodies for the new coronavirus. Once the plasma is donated, it can take one of two paths: be directly transfused into patient or used to make a potential plasma-derived medicine.
DONATION
Patients who have recovered from COVID-19 donate their blood plasma. This plasma contains antibodies that could help the immune system fight the new coronavirus.
SCREENING
Plasma is tested for any transmittable viruses, as well as for compatibility between donor and recipient.
PATH 1
DIRECT TRANSFUSION
TRANSFUSION
Afer the plasma passes screening, it is transfused directly to patients experiencing serious complications from COVID-19. Patient treatment is individualized
EVALUATION /CLINICAL TRIALS
The efficacy of these transfusions is currently being studied in multiple trials occurring throughout the US.
AVAILABILITY
If approved, the potential medicines will be ready for use. The timing depends on many factors, but in the best-case scenario, they could be available sometime this year, making them among the earliest approved scalable treatment options. They would serve as a bridge until a vaccine is readily available.
PATH 2
PLASMA-DERIVED MEDICINE
PATIENT THERAPY DEVELOPMENT
Plasma is sent to manufacturing facilities. There, it is pooled, processed to remove other antibodies and inactivate viruses, and purified to create a “hyperimmune globulin” that contains a reliably consistent amount of antibodies.
EVALUATION /CLINICAL TRIALS
Once enough plasma is collected and processed, the potential medicine will go into clinical trials. The trials will study whether it safely and effectively treats people at risk for serious complications from COVID-19.
APPROVAL
If regulatory bodies like the US Food and Drug Administration (FDA) and European Medicines Agency (EMA) determine that the potential medicine is both safe and effective, it could be approved to treat patients at risk for serious complications from COVID-19. Companies are also discussing potential use across the world with other national health authorities.
AVAILABILITY
If approved, the potential medicines will be ready for use. The timing depends on many factors, but in the best-case scenario, they could be available sometime this year, making them among the earliest approved scalable treatment options. They would serve as a bridge until a vaccine is readily available.
Translation - Spanish DOS FORMAS EN LAS QUE EL PLASMA CONVALECIENTE PODRÍA AYUDAR A COMBATIR LA COVID-19
El plasma sanguíneo de las personas que se han recuperado de la COVID-19 puede ser clave para luchar contra la enfermedad ya que contiene anticuerpos del nuevo coronavirus. Una vez donado el plasma, puede tomar uno de dos caminos posibles: ser directamente transfundido a los pacientes o ser utilizado para la creación de potenciales medicamentos derivados del plasma.
DONACIÓN
Los pacientes recuperados de la COVID-19 donan su plasma sanguíneo.
Este plasma contiene anticuerpos que podrían ayudar a que el sistema inmunológico combata el nuevo coronavirus.
PRUEBA
El plasma se analiza para detectar cualquier virus transmisible, como así también la compatibilidad entre donante y receptor.
CAMINO 1
TRANSFUSIÓN DIRECTA
TRANSFUSIÓN
Luego de que el plasma pasa las pruebas, es transfundido directamente a los pacientes que experimentan complicaciones serias por la COVID-19. El tratamiento para cada paciente es personalizado.
EVALUACIÓN/ENSAYOS CLÍNICOS
En la actualidad, se está analizando la eficacia de estas transfusiones en todo EE. UU. mediante múltiples ensayos.
DISPONIBILIDAD
De ser aprobados, los potenciales medicamentos estarán listos para ser utilizados.
El tiempo depende de varios factores, pero en el mejor de los casos, podrían estar disponibles dentro de este año, convirtiéndolas en una de las opciones de tratamiento escalable aprobadas con mayor celeridad.
CAMINO 2
MEDICAMENTOS DERIVADOS DEL PLASMA
DESARROLLO DEL TRATAMIENTO PARA EL PACIENTE
El plasma se envía a los centros de elaboración.
Allí el plasma se reúne, se procesa para eliminar otros anticuerpos e inactivar otros virus, y se purifica para crear una "globulina hiperinmune" que contenga una cantidad estable de anticuerpos.
EVALUACIÓN/ENSAYOS CLÍNICOS
Una vez recolectado y procesado suficiente plasma, el potencial medicamento pasará por los ensayos clínicos correspondientes. Los ensayos analizarán si es seguro y efectivo para tratar a las personas en riesgo con complicaciones graves por la COVID-19.
APROBACIÓN
Si los organismos regulatorios tales como la Administración de Alimentos y Medicamentos de los Estados Unidos (FDA) and la Agencia Europea de Medicamentos (EMA) determinan que el potencial medicamento es tanto seguro como efectivo, podría ser aprobado para tratar pacientes en riesgo con complicaciones producidas por la COVID-19. Las empresas también están analizando junto con otras autoridades nacionales de salud el posible uso en el resto del mundo.
DISPONIBILIDAD
De ser aprobados, los potenciales medicamentos estarán listos para ser utilizados.
El tiempo depende de varios factores, pero en el mejor de los casos, podrían estar disponibles dentro de este año, convirtiéndolas en una de las opciones de tratamiento escalable aprobadas con mayor celeridad. Estos medicamentos acortarían la brecha hasta tanto una vacuna se encuentre disponible.
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Years of experience: 2. Registered at ProZ.com: Dec 2021.
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ABOUT ME
My name is Marianela Grazzini and I’m a Literary and Technical-Scientific Translator, with a vastknowledge of Anglophone culture and language.
Currently, I’m working as a Freelance Translator, MTPE, Editor and Proofreader.
My areas of specialization include IT, Healthcare and Medicine, Marketing and Editorial (Journalistic/Webtoons) related contents.
My aim is to develop myself professionally, keep on broadening my expertise in the field and provide accurate and reliable language services to individuals, companies, professional service providers and other organizations.
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