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Source text - English Acute dystonia associated with metoclopramide: a case presentation
Although the underlying neurochemical anomaly is not known, it has been implicated that the pathophysiology of dystonia may be associated with abnormal dopaminergic activity in basal ganglia. Although it is frequently seen with classical antipsychotics, some dopaminergic agents such as metoclopramide may cause this side effect. In this paper, we present a 17 years old woman under treatment with metoclopramide in therapeutic doses, who was referred to our hospital because of acute dystonia.
Translation - Turkish Metoklopramidle gelişen akut distoni: Bir olgu sunumu
Distonide, altta yatan nörokimyasal patoloji bilinmemekle birlikte, bazal gangliyonlardaki dopaminerjik aktivi¬tede görülen anormalliklerin etkili olduğu üzerinde durulmaktadır. Çoğunlukla klasik antipsikotiklerle ortaya çıkan bir yan etki olmakla birlikte, metaklopramid gibi dopaminerjik yolak üzerinde etkili olabilecek çeşitli ilaç¬ların alınmasıyla da ortaya çıkabilir. Çalışmamızda, terapötik dozda metoklopramid tedavisi almakta iken, akut distonik reaksiyon gelişmesi nedeniyle polikliniğimize yönlendirilen 17 yaşında bir olgu sunulmuştur.
English to Turkish (ÜDS - TURKEY) English to Turkish (Çukurova Üniversitesi)
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