Glossary entry

English term or phrase:

the ester configuration flip

French translation:

l'inversion de configuration de l'ester

Added to glossary by liz askew
Oct 17 09:02
27 days ago
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English term

the ester configuration flip

English to French Tech/Engineering Biology (-tech,-chem,micro-) Brevet pharma
Step3, under strong base conditions, carrying out the ester configuration flip of the (2R,3S)-3-amino-bicyclo[2.2.2]octane-2-carboxylate to give the (2S,3S)-3-amino-bicyclo[2.2.2]octane-2-carboxylate, the strong base comprises at least one selected from the group consisting of sodium tert-butoxide, sodium tert-amylate, lithium diisopropylamide, lithium bis(trimethylsilyl)amide, sodium bis(trimethylsilyl)amide and potassium bis(trimethylsilyl)amide
References
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Change log

Oct 22, 2024 12:48: liz askew Created KOG entry

Proposed translations

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2 hrs
Selected

l'inversion de configuration de l'ester

La stéréoisomérie - TS - Cours Physique-Chimie
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Pour les différencier, il faut identifier, dans les deux molécules, les atomes de carbone qui ont subi une inversion de configuration. Si, d'une molécule à l' ...

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Note added at   2 godz. (2024-10-17 11:28:42 GMT)
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https://www.google.co.uk/search?as_q=inversion de configurat...
Peer comment(s):

neutral UberTranslate : 2R,3S → 2S,3S n'est pas une inversion mais un changement/torsion d'axe...
2 hrs
https://www.merriam-webster.com/thesaurus/invert
agree Lionel-N : https://chimieorganique.faidherbe.org/sterdyn.htm
1 day 4 hrs
Merci!
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4 KudoZ points awarded for this answer. Comment: "Merci à tous"
15 mins

Changement de configuration (stéréochimique) de l'ester

Changement de configuration (stéréochimique) de l'ester
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Reference comments

2 hrs
Reference:

see

https://en.wikipedia.org/wiki/Ring_flip
In organic chemistry, a ring flip (also known as a ring inversion or ring reversal) is the interconversion of cyclic conformers that have equivalent ring shapes (e.g., from a chair conformer to another chair conformer) that results in the exchange of nonequivalent substituent positions.[1] The overall process generally takes place over several steps, involving coupled rotations about several of the molecule's single bonds, in conjunction with minor deformations of bond angles. Most commonly, the term is used to refer to the interconversion of the two chair conformers of cyclohexane derivatives, which is specifically referred to as a chair flip, although other cycloalkanes and inorganic rings undergo similar processes.



Chair flipAs stated above, a chair flip is a ring inversion specifically of cyclohexane (and its derivatives) from one chair conformer to another, often to reduce steric strain. The term, "flip" is misleading, because the direction of each carbon remains the same; what changes is the orientation. A conformation is a unique structural arrangement of atoms, in particular one achieved through the rotation of single bonds.[2] A conformer is a conformational isomer, a blend of the two words.

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Note added at   2 godz. (2024-10-17 11:24:57 GMT)
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Conformation cyclohexane
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L'interconversion des conformères de type chaise est appelée inversion de cycle ( ring flipping) ou inversion de chaise (chair-flipping) . Les liaisons ...

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Note added at   2 godz. (2024-10-17 11:26:31 GMT)
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inversion de configuration??


https://cdnsciencepub.com/doi/10.1139/v99-152
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