Jakub Rychter, Ph.D.
With a PhD in Medical Biology and professional experience in regulatory affairs and medical research, I specialize in delivering precise and reliable translations tailored to the healthcare and life sciences sectors. From medical reports and research papers to regulatory documents and pharmaceutical content, my expertise ensures accuracy and cultural sensitivity in every project.

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Profile:
● PhD in Physiology and Immunology
● Native proficiency in English and Dutch acquired growing up in a bilingual household in the Netherlands.
● Near-native proficiency in German acquired growing up in Germany
● Over eight years of work experience in biomedical research in academia
● Experience in writing, editing, reviewing and publishing of medical research publications
● Author of several research publications in major international journals in the field of surgery, gastroenterology, parasitology, and physiology


Work Experience:
● Freelance translator since 2011
● Guest Professor, Pompeu Fabra University, Mataro, Spain
● Dissertation director, Autonomous University of Barcelona, Barcelona, Spain (link)
● Postdoctoral researcher, Autonomous University of Barcelona, Barcelona, Spain
● PhD candidate, Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, the Netherlands
● Quality Assurance Coordinator, Department of pharmaceutical affairs, Sandoz/Novartis group, Almere, the Netherlands

Education:
● Ph.D: Physiology and Immunology, Utrecht University, the Netherlands
● M.Sc: Medical Biology, Radboud University, the Netherlands
● B.Sc: Medical Biology, Radboud University, the Netherlands

My medical translation website


Member of the American Translators Association (ATA)

My ATA profile

ResearchGate:

My ResearchGate profile


LinkedIn:

My LinkedIn profile


Authored publications:

Mast cell degranulation inhibits motor patterns of human ileum and sigmoid colon in vitro: relevance for postoperative ileus. Rychter J, Ortega O, Berdun S, Arenas C, Lopez I, Espin F, Vergara P, Clavé P. Neurogastroenterol Motil. 2015 May 13. doi: 10.1111/nmo.12589. [Epub ahead of print]

Colonic smooth muscle cells and colonic motility patterns as a target for irritable bowel syndrome therapy: mechanisms of action of otilonium bromide. J Rychter, F Espín, D Gallego, P Vergara, M Jiménez, P Clavé. Therap Adv Gastroenterol 7(4):156-66(2014)

Intestinal inflammation in postoperative ileus: pathogenesis and therapeutic targets. J Rychter, P Clavé. Gut 62(11):1534-5(2013)

CGRP1 receptor activation induces piecemeal release of protease-1 from mouse bone marrow-derived mucosal mast cells. J Rychter, L van Nassauw, J-P Timmermans, LMA Akkermans, RHS Westerink, ABA Kroese. Neurogastroenterology and Motility 23(2):57-68(2011)

Impairment of intestinal barrier and secretory function as well as egg excretion during intestinal schistosomiasis occur independently of mouse mast cell protease-1. J Rychter, L. van Nassauw, JK Brown, E van Marck, PA Knight, HRP Miller, ABA Kroese, J-P Timmermans. Parasite Immunology 32:221-31(2010)

Pretreatment but not treatment with probiotics abolishes mouse intestinal barrier dysfunction in acute pancreatitis.J Rychter, L van Minnen, A Verheem, H Timmerman, G Rijkers, M Schipper, H Gooszen, L Akkermans, ABA Kroese. Surgery 145:157-67(2009)

On the contribution of mucosal mast cells to the regulation of mouse intestinal barrier function. J Rychter, Doctoral thesis (2010).

Co-authored publications:

Effects of nerve growth factor antagonist K252a on peritoneal mast cell degranulation. Berdun S, Rychter J, Vergara P. Am J Physiol Gastrointest Liver Physiol. 2015 Nov 15;309(10):G801-6.

Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery.Berdún S, Bombuy E, Estrada O, Mans E, Rychter J, Clavé P, Vergara P. Neurogastroenterol Motil. 2015 Jun;27(6):764-74.

Surgical intestinal manipulation increases gene expression of TrkA, CGRP, and PAR-2 IN dorsal root ganglia in the rat. Berdún S, Rychter J, Vergara P. Neurogastroenterol Motil. 2016 Jun;28(6):816-26. Epub 2016 Feb 22.

Immunoglobulin-free light chains reduce in an antigen-specific manner the rate of rise of action potentials of mouse non-nociceptive dorsal root ganglion neurons. Rijnierse A, Kraneveld AD, Salemi A, Zwaneveld S, Goumans AP, Rychter JW, Thio M, Redegeld FA, Westerink RH, Kroese AB. J Neuroimmunol. 2013 Nov 15;264(1-2):14-23.

Corticotropin-releasing factor, urocortin 1, and their receptors in the mouse spinal cord. Korosi A, Kozicz T, Rychter J, Veening JG, Olivier B, Roubos EW. J Comp Neurol. 2007 Jun 20;502(6):973-89.